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Restylane® adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).
Restylane® can also add fullness and definition to lips in patients over 21 years, providing natural-looking and lasting results with just one treatment. In fact, Restylane® and Restylane-L are the only FDA-approved dermal fillers for lip enhancement in patients over 21 years.
The Restylane family can also be used in other moderate to severe facial wrinkles such as lipstick lines— the area just below the nose and above the upper lip; the corners of the mouth; and marionette lines—the area that extends downward from the corners of the mouth to the jawline.
Restylane® works immediately by adding volume to smooth away wrinkles. A clear gel formulation of hyaluronic acid, Restylane is specifically formulated to act like your body's own hyaluronic acid. So, you can use Restylane® to visibly reduce moderate to severe facial wrinkles and folds, and to add fullness to your lips.
Injectables
The Restylane® family of products instantly adds volume to help restore youthful contours, so you'll see results immediately following your treatment. There is little to no downtime.
In a clinical study of laugh lines (nasolabial folds), at least 95% of patients treated with Restylane continued to see results for up to 18 months after initial treatment when patients returned for a follow-up treatment at four and a half or nine months.
In a clinical study of Restylane for lip enhancement, Restylane provided results for up to 6 months with one treatment.
After your treatment, you might have some swelling, redness, pain, bruising, or tenderness. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14 days in lips. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years.
The Restylane family of products should not be used by people with previous bad allergies, particularly to microorganisms known as gram-positive bacteria, or by people with serious allergies to drugs that have previously required in-hospital treatment. These products should not be used by people with bleeding disorders. Products should not be injected anywhere except the skin, just under the skin (Perlane and Perlane-L only), or in the lips (Restylane and Restylane-L only). Restylane-L and Perlane-L should not be used by anyone with a known allergy to lidocaine.
To avoid bruising and bleeding, you should not use the products if you have recently used drugs that thin your blood or prevent clotting. Products should not be used during pregnancy, when breastfeeding, or in patients under 18 years for nasolabial folds and under 21 years for lips.
The Restylane family of products includes Restylane, Restylane-L®, Perlane®, and Perlane-L®. These products can be used individually to add volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds or laugh lines); lipstick lines (the area just below the nose and above the upper lip); the corners of the mouth; and marionette lines (the area that extends downward from the corners of the mouth to the jawline). Restylane and Restylane-L may also be used for lip enhancement in patients over 21 years.
The safety and effectiveness of products in the Restylane family for the treatment of anatomic regions other than nasolabial folds and lips (Restylane and Restylane-L only) have not been established in controlled clinical studies. Patients should be limited to 6.0 mL per treatment of moderate to severe facial wrinkles and folds. Patients should be limited to 1.5 mL per lip per treatment (Restylane and Restylane-L only). If a volume of more than 3 mL total is needed to achieve optimal correction for lip enhancement, a follow-up treatment session is recommended.
Restylane injectable gel has been clinically proven to provide results that last up to 18 months in the laugh lines (nasolabial folds), with only one follow-up treatment at either 4.5 or nine months. Your healthcare professional can work with you to help you establish your Restylane Regimen. Perlane injectable gel results may last up to six months after a single treatment.
The Restylane family of products instantly adds volume to help restore youthful contours, so you'll see results immediately following your treatment.
Due to the individual needs of each patient, it is important to discuss your full correction with your healthcare professional. However, in a clinical study where patients received full correction for their nasolabial folds (lines from the nose to the corners of the mouth) during initial treatment in the Restylane Regimen, the average volume was 2 to 3 mL per patient.
After treatment, you might have some swelling, redness, pain, bruising, or tenderness. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14 days in lips. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years.
