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SkinCeuticals® A.G.E. Interrupter Advanced

Concentrated corrective cream helps reverse visible signs of aging impacted by glycation and collagen decline

Authorized Physician Reseller of SkinCeuticals



A.G.E. Interrupter Advanced is a multi-corrective cream clinically proven to improve visible signs of accelerated aging by preventing the multi-phase glycation process and supporting collagen integrity. Backed by 15+ years of glycation expertise and formulated with more potent and efficacious ingredients than its predecessor (A.G.E. Interrupter), this next-generation cream goes beyond traditional anti-aging skincare to smooth visible wrinkles, restore firmness, and enhance skin's radiance to counter dull and sallow tone. A.G.E. Interrupter Advanced features a rich, dry-finish texture, is suitable for all skin types and tones, and can be used alone or in conjunction with other corrective treatments and moisturizers.

What is Glycation?

Glycation, a key factor of intrinsic aging, occurs when excess glucose molecules bind to structural proteins, such as collagen and elastin. This multi-phase process is accelerated by external aggressors, including UV and pollution, which cause oxidative stress. As glycation progresses, crosslinking occurs and forms a ladder-like structure, causing collagen and elastin to become rigid and brittle, and resulting in Advanced Glycation End-Products (A.G.E.s).
A.G.E.s further damage skin cells, degrading their reparative ability and triggering
an inflammatory response.

AGE Interrupter Adv Results


Once or twice daily, massage a thin, even layer onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.


Helps correct visible wrinkles and laxity by stimulating collagen VII and supporting its environment, delivering 6x more than the minimum effective dose known to activate glycosaminoglycans (GAGs).

Antioxidant blend of blueberry and pomegranate extracts helps inhibit protein glycation, including UV-induced glycation, and protect against free radical damage.

Therapeutic anti-inflammatory helps enhance the skin's natural radiance to counter dull and sallow tone, which may be linked to A.G.E. accumulation.




  • Smooths visible wrinkles
  • Helps restore skin firmness
  • Comforts dry, aging skin
  • Enhances skin's natural radiance to visibly diminish dull and sallow tone
  • Reduces inflammatory responses linked to A.G.E. formation

Problem or Condition

Wrinkles, Fine Lines, Sagging/Loose Skin, Dull/Tired Skin

Skin Type

Combination Skin, Aging Skin, Normal Skin, Sensitive Skin, Dry Skin
Size - 1.7 oz


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SkinCeuticals® A.G.E. Interrupter Advanced

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